Development of Novel Methodology for Rapid Conjugated Oligosaccharide Synthesis
نویسندگان
چکیده
منابع مشابه
[Development of novel methodology for rapid conjugated oligosaccharide synthesis].
Glycosylation is one of the most important post-translation modifications of proteins, which affects biological activities by way of controlling higher order structure. Recently, the novel structure of glycoprotein, namely C-glycosyl protein was identified in various proteins. The first total synthesis of the naturally occurring C-glycosyl amino acid and peptide was achieved. The mannose and tr...
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A variety of C-disaccharides have been selectively and expeditiously synthesized through the so-called tether approach. Jntroduction . 'Oligosacch&ides are involved in a increasing number of biological processes. This has stimulated the development of selective methods for the synthesis of such complex molecules. Among others, the imidate. procedure that we have discovered (ref. l), and which h...
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ژورنال
عنوان ژورنال: YAKUGAKU ZASSHI
سال: 2002
ISSN: 0031-6903,1347-5231
DOI: 10.1248/yakushi.122.295